Factors associated with detection of measles-specific immunoglobulin M (IgM-positive) in Cte dIvoire from 2015 to 2019: A nested case-control study from a measles national surveillance programme

Measles outbreaks are regularly reported in Côte d’Ivoire districts although on-going measles vaccination coverage has increased. The objective was to identify the factors associated with IgM-positive a population suspected measles. A case-control study nested national surveillance of 9337 registered cases from 2015 2019 d'Ivoire conducted for identification laboratory-confirmed case-based independent detection IgM blood were determined logistic regression. Among cases, 88.84% had samples taken test antibody. proportion IgM-positivity 10.03% among 8295 tested at reference laboratory. median age four years (y) an interquartile range (IQR) [1.5-9 years]. majority subjects (71.28%) aged 1 15 years. Of subjects, 52.05% unknown status. presence were: Unvaccinated status against (adjusted odds-ratio [aOR]=2.82, 95% confidence interval (CI) 2.19 3.64), increasing (aOR(95% CI): 1.37(1.06 1.78), 1.54(1.18 2.00), 1.56(1.14 2.12) groups 1-5 years, 5 +, respectively compared group 0 year, and health regions residence located west aOR ranged between 1.68 (Haut Sassandra) 2.87 (Marahoue). Interventions considering will help control spread Cote d’Ivoire. Key word: Measles-specific M-immunoglobulin, measles, vaccination, regression, programme,